l am about to purchase a 2001 IS 300 with 101,000 miles. Is that considered high mileage?

Yes, but it should be fine. Make sure it has had a tune-up done to it though. That would be evidence of the person actually taking care of the car and it will save you a couple hundred. Before you buy a high mileage luxury car make sure you can afford to maintain it.

Check out edmunds.com and see what the cost to own on the car is.

No. It is average as they say you put on between 12K -15K miles a year. So using 15K as a base, your 7 year old Lexus would be at 105K. Plus, that model is very reliable. Just be sure the normal services were done as well as the timing belt.

Why ''two'' thumbs down? That is not high miles on a Toyota powertrain!

Its at the high end of the normal mileage range so not really high mileage for its age.

Make sure you get the vehicle checked out by an independent mechanic before you hand over any money though. You want to make sure its in good mechanical condition and not just shined up on the outside.

on an american car.. yes that is high mileage... on a Lexus, that is absolutely nothing. it will run you an easy 300k miles as long as you keep up with regular maintance.

yes but it is an import / high end toyota so it should be just fine
just make sure you're not over paying for it.

01 vehicle should only have about 85,xxx~95,xxx