l havea 2000ES 300 Lexus and would like to know that by changing the regular spark plugs to a 4 ground electro spark plus would get more miles per gallon and which spark plug is better to use? is it DENSO or BOSCH platnium?

Denso is the best plug for a Toyota product.
Bosch plugs should be used in European vehicles only.BTW,you will achieve best fuel economy with original type plugs.Your car was built with Denso plugs,purchase the original type for best performance and fuel economy.

If ur LEXUS ES300 engine is in good tune & not over 100,000 miles, the OEM Nippondenso spark plugs r probably better suited for ur car. Of course, all maintenance items should be followed carefully in order to avoid any malfunctions, misfires or stumbling. We r assuming that u will observe the correct spark plug heat range, plug gap, & secondary ignition high tension parameters. The two, three, & four ground electrode plugs have no real advantage on a well tuned engine.

Stay with the Denso or NGK plugs. Our Toyotas do not play well with Bosch plugs for some reason

NGK all the way